The role of ICOS in the development of CD4 T cell help and the reactivation of memory T cells

We have addressed the role of the inducible costimulator (ICOS) in the development of T cell help for B cells and in the generation, survival and reactivation of memory CD4 T cells and B cells. We find that while T cell help for all antibody isotypes (including IgG2c) is impaired in ICOS knockout (I...

Descripción completa

Detalles Bibliográficos
Autores principales: Mahajan, Simmi, Cervera, Ana, MacLeod, Megan, Fillatreau, Simon, Perona-Wright, Georgia, Meek, Stephen, Smith, Andrew, MacDonald, Andrew, Gray, David
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2007
Materias:
Cellular immune response
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699381/
https://www.ncbi.nlm.nih.gov/pubmed/17549732
http://dx.doi.org/10.1002/eji.200636661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699381/
https://www.ncbi.nlm.nih.gov/pubmed/17549732
http://dx.doi.org/10.1002/eji.200636661

Ejemplares similares