TAK1 is an essential regulator of BMP signalling in cartilage

TGFβ activated kinase 1 (TAK1), a member of the MAPKKK family, controls diverse functions ranging from innate and adaptive immune system activation to vascular development and apoptosis. To analyse the in vivo function of TAK1 in cartilage, we generated mice with a conditional deletion of Tak1 drive...

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Detalles Bibliográficos
Autores principales: Shim, Jae-Hyuck, Greenblatt, Matthew B, Xie, Min, Schneider, Michael D, Zou, Weiguo, Zhai, Bo, Gygi, Steven, Glimcher, Laurie H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699391/
https://www.ncbi.nlm.nih.gov/pubmed/19536134
http://dx.doi.org/10.1038/emboj.2009.162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699391/
https://www.ncbi.nlm.nih.gov/pubmed/19536134
http://dx.doi.org/10.1038/emboj.2009.162

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