Cell Cycle Regulating Kinase Cdk4 as a Potential Target for Tumor Cell Treatment and Tumor Imaging

The cyclin-dependent kinase (Cdk)-cyclin D/retinoblastoma (pRb)/E2F cascade, which controls the G1/S transition of cell cycle, has been found to be altered in many neoplasias. Inhibition of this pathway by using, for example, selective Cdk4 inhibitors has been suggested to be a promising approach fo...

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Detalles Bibliográficos
Autores principales: Graf, Franziska, Koehler, Lena, Kniess, Torsten, Wuest, Frank, Mosch, Birgit, Pietzsch, Jens
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699447/
https://www.ncbi.nlm.nih.gov/pubmed/19551155
http://dx.doi.org/10.1155/2009/106378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699447/
https://www.ncbi.nlm.nih.gov/pubmed/19551155
http://dx.doi.org/10.1155/2009/106378

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