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Lactate Dehydrogenase-Elevating Virus Induces Systemic Lymphocyte Activation via TLR7-Dependent IFNα Responses by Plasmacytoid Dendritic Cells

BACKGROUND: Lactate dehydrogenase-elevating virus (LDV) is a natural infectious agent of mice. Like several other viruses, LDV causes widespread and very rapid but transient activation of both B cells and T cells in lymphoid tissues and the blood. The mechanism of this activation has not been fully...

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Detalles Bibliográficos
Autores principales: Ammann, Christoph G., Messer, Ronald J., Peterson, Karin E., Hasenkrug, Kim J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699471/
https://www.ncbi.nlm.nih.gov/pubmed/19568424
http://dx.doi.org/10.1371/journal.pone.0006105