Prion Protein (PrP) Knock-Out Mice Show Altered Iron Metabolism: A Functional Role for PrP in Iron Uptake and Transport

Despite overwhelming evidence implicating the prion protein (PrP) in prion disease pathogenesis, the normal function of this cell surface glycoprotein remains unclear. In previous reports we demonstrated that PrP mediates cellular iron uptake and transport, and aggregation of PrP to the disease caus...

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Detalles Bibliográficos
Autores principales: Singh, Ajay, Kong, Qingzhong, Luo, Xiu, Petersen, Robert B., Meyerson, Howard, Singh, Neena
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699477/
https://www.ncbi.nlm.nih.gov/pubmed/19568430
http://dx.doi.org/10.1371/journal.pone.0006115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699477/
https://www.ncbi.nlm.nih.gov/pubmed/19568430
http://dx.doi.org/10.1371/journal.pone.0006115

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