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Replication Independent Formation of Extrachromosomal Circular DNA in Mammalian Cell-Free System

Extrachromosomal circular DNA (eccDNA) is a pool of circular double stranded DNA molecules found in all eukaryotic cells and composed of repeated chromosomal sequences. It was proposed to be involved in genomic instability, aging and alternative telomere lengthening. Our study presents novel mammali...

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Detalles Bibliográficos
Autores principales: Cohen, Zoya, Lavi, Sara
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699479/
https://www.ncbi.nlm.nih.gov/pubmed/19568438
http://dx.doi.org/10.1371/journal.pone.0006126