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Dramatic effect of single-base mutation on the conformational dynamics of human telomeric G-quadruplex
Guanine-rich DNA sequences can form G-quadruplexes. These four-stranded structures are known to form in several genomic regions and to influence certain biological activities. Sometimes, the instability of G-quadruplexes causes the abnormal biological processes. Mutation is a culprit for the destabi...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699503/ https://www.ncbi.nlm.nih.gov/pubmed/19359361 http://dx.doi.org/10.1093/nar/gkp216 |