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Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto-Regulation

The RNA-binding protein, HuR, is involved in the stabilization of AU-rich element-containing mRNAs with products that are involved in cell-cycle progression, cell differentiation and inflammation. We show that there are multiple polyadenylation variants of HuR mRNA that differ in their abundance, us...

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Detalles Bibliográficos
Autores principales: Al-Ahmadi, Wijdan, Al-Ghamdi, Maha, Al-Haj, Latifa, Al-Saif, Maher, Khabar, Khalid S. A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699509/
https://www.ncbi.nlm.nih.gov/pubmed/19359363
http://dx.doi.org/10.1093/nar/gkp223