Cargando…
Crystal structure of the ββα-Me type II restriction endonuclease Hpy99I with target DNA
The ββα-Me restriction endonuclease (REase) Hpy99I recognizes the CGWCG target sequence and cleaves it with unusual stagger (five nucleotide 5′-recessed ends). Here we present the crystal structure of the specific complex of the dimeric enzyme with DNA. The Hpy99I protomer consists of an antiparalle...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699513/ https://www.ncbi.nlm.nih.gov/pubmed/19380375 http://dx.doi.org/10.1093/nar/gkp228 |