Rapid Cdc13 turnover and telomere length homeostasis are controlled by Cdk1-mediated phosphorylation of Cdc13

Budding yeast telomerase is mainly activated by Tel1/Mec1 (yeast ATM/ATR) on Cdc13 from late S to G2 phase of the cell cycle. Here, we demonstrated that the telomerase-recruitment domain of Cdc13 is also phosphorylated by Cdk1 at the same cell cycle stage as the Tel1/Mec1-dependent regulation. Phosp...

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Detalles Bibliográficos
Autores principales: Tseng, Shun-Fu, Shen, Zih-Jie, Tsai, Hung-Ji, Lin, Yi-Hsuan, Teng, Shu-Chun
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699520/
https://www.ncbi.nlm.nih.gov/pubmed/19359360
http://dx.doi.org/10.1093/nar/gkp235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699520/
https://www.ncbi.nlm.nih.gov/pubmed/19359360
http://dx.doi.org/10.1093/nar/gkp235

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