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Generation of Monoclonal Antibodies against Highly Conserved Antigens
BACKGROUND: Therapeutic antibody development is one of the fastest growing areas of the pharmaceutical industry. Generating high-quality monoclonal antibodies against a given therapeutic target is very crucial for the success of the drug development. However, due to immune tolerance, some proteins t...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699554/ https://www.ncbi.nlm.nih.gov/pubmed/19564921 http://dx.doi.org/10.1371/journal.pone.0006087 |