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Generation of Monoclonal Antibodies against Highly Conserved Antigens

BACKGROUND: Therapeutic antibody development is one of the fastest growing areas of the pharmaceutical industry. Generating high-quality monoclonal antibodies against a given therapeutic target is very crucial for the success of the drug development. However, due to immune tolerance, some proteins t...

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Detalles Bibliográficos
Autores principales: Zhou, Hongzhe, Wang, Yunbo, Wang, Wei, Jia, Junying, Li, Yuan, Wang, Qiyu, Wu, Yanfang, Tang, Jie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699554/
https://www.ncbi.nlm.nih.gov/pubmed/19564921
http://dx.doi.org/10.1371/journal.pone.0006087