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Synergistic Activation of HIV-1 Expression by Deacetylase Inhibitors and Prostratin: Implications for Treatment of Latent Infection

The persistence of transcriptionally silent but replication-competent HIV-1 reservoirs in Highly Active Anti-Retroviral Therapy (HAART)-treated infected individuals, represents a major hurdle to virus eradication. Activation of HIV-1 gene expression in these cells together with an efficient HAART ha...

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Detalles Bibliográficos
Autores principales: Reuse, Sophie, Calao, Miriam, Kabeya, Kabamba, Guiguen, Allan, Gatot, Jean-Stéphane, Quivy, Vincent, Vanhulle, Caroline, Lamine, Aurélia, Vaira, Dolores, Demonte, Dominique, Martinelli, Valérie, Veithen, Emmanuelle, Cherrier, Thomas, Avettand, Véronique, Poutrel, Solène, Piette, Jacques, de Launoit, Yvan, Moutschen, Michel, Burny, Arsène, Rouzioux, Christine, De Wit, Stéphane, Herbein, Georges, Rohr, Olivier, Collette, Yves, Lambotte, Olivier, Clumeck, Nathan, Van Lint, Carine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699633/
https://www.ncbi.nlm.nih.gov/pubmed/19564922
http://dx.doi.org/10.1371/journal.pone.0006093