Physico-Chemical Characteristics of Lipoplexes Influence Cell Uptake Mechanisms and Transfection Efficacy

BACKGROUND: Formulation of DNA/cationic lipid complexes (lipoplexes) designed for nucleic acid delivery mostly results in positively charged particles which are thought to enter cells by endocytosis. We recently developed a lipoplex formulation called Neutraplex that allows preparation of both catio...

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Detalles Bibliográficos
Autores principales: Resina, Sarah, Prevot, Paul, Thierry, Alain R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699663/
https://www.ncbi.nlm.nih.gov/pubmed/19557145
http://dx.doi.org/10.1371/journal.pone.0006058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699663/
https://www.ncbi.nlm.nih.gov/pubmed/19557145
http://dx.doi.org/10.1371/journal.pone.0006058

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