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Efficacy and Safety of the Human Glucagon-Like Peptide-1 Analog Liraglutide in Combination With Metformin and Thiazolidinedione in Patients With Type 2 Diabetes (LEAD-4 Met+TZD)

OBJECTIVE: To determine the efficacy and safety of liraglutide (a glucagon-like peptide-1 receptor agonist) when added to metformin and rosiglitazone in type 2 diabetes. RESEARCH DESIGN AND METHODS: This 26-week, double-blind, placebo-controlled, parallel-group trial randomized 533 subjects (1:1:1)...

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Detalles Bibliográficos
Autores principales: Zinman, Bernard, Gerich, John, Buse, John B., Lewin, Andrew, Schwartz, Sherwyn, Raskin, Philip, Hale, Paula M., Zdravkovic, Milan, Blonde, Lawrence
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699702/
https://www.ncbi.nlm.nih.gov/pubmed/19289857
http://dx.doi.org/10.2337/dc08-2124