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Microalbuminuria in Type 1 Diabetes Is Associated With Enhanced Excretion of the Endocytic Multiligand Receptors Megalin and Cubilin

OBJECTIVE: Proteinuria is the hallmark of diabetic nephropathy; yet, glomerular histology does not fully explain mechanisms contributing to proteinuria. Our objective was to identify proteins in the urine of individuals with type 1 diabetes and microalbuminuria that might implicate a mechanistic pat...

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Detalles Bibliográficos
Autores principales: Thrailkill, Kathryn M., Nimmo, Teresa, Bunn, R. Clay, Cockrell, Gael E., Moreau, Cynthia S., Mackintosh, Samuel, Edmondson, Ricky D., Fowlkes, John L.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699744/
https://www.ncbi.nlm.nih.gov/pubmed/19366958
http://dx.doi.org/10.2337/dc09-0112