NOD × 129.H2(g7) Backcross Delineates 129S1/SvImJ-Derived Genomic Regions Modulating Type 1 Diabetes Development in Mice

OBJECTIVE: Introduction of genes targeted in 129/Sv embryonic stem (ES) cells into NOD mice brings about linked genes that may modulate type 1 diabetes. Our objective was to identify 129S1/SvJ non-MHC regions contributing type 1 diabetes resistance or susceptibility in backcross to NOD/LtJ. RESEARCH...

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Detalles Bibliográficos
Autores principales: Leiter, Edward H., Reifsnyder, Peter C., Wallace, Racheal, Li, Renhua, King, Benjamin, Churchill, Gary C.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699846/
https://www.ncbi.nlm.nih.gov/pubmed/19336673
http://dx.doi.org/10.2337/db09-0120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699846/
https://www.ncbi.nlm.nih.gov/pubmed/19336673
http://dx.doi.org/10.2337/db09-0120

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