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Lack of Type VIII Collagen in Mice Ameliorates Diabetic Nephropathy

OBJECTIVE: Key features of diabetic nephropathy include the accumulation of extracellular matrix proteins. In recent studies, increased expression of type VIII collagen in the glomeruli and tubulointerstitium of diabetic kidneys has been noted. The objectives of this study were to assess whether typ...

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Detalles Bibliográficos
Autores principales: Hopfer, Ulrike, Hopfer, Helmut, Meyer-Schwesinger, Catherine, Loeffler, Ivonne, Fukai, Naomi, Olsen, Bjorn R., Stahl, Rolf A.K., Wolf, Gunter
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699847/
https://www.ncbi.nlm.nih.gov/pubmed/19401424
http://dx.doi.org/10.2337/db08-0183