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CD4(+)CD25(+) T-Cells Control Autoimmunity in the Absence of B-Cells

OBJECTIVE: Tumor necrosis factor ligand family members B-cell–activating factor (BAFF) and a proliferation-inducing ligand (APRIL) can exert powerful effects on B-cell activation and development, type 1 T-helper cell (Th1) immune responses, and autoimmunity. We examined the effect of blocking BAFF a...

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Detalles Bibliográficos
Autores principales: Mariño, Eliana, Villanueva, Jeanette, Walters, Stacey, Liuwantara, David, Mackay, Fabienne, Grey, Shane T.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699852/
https://www.ncbi.nlm.nih.gov/pubmed/19336675
http://dx.doi.org/10.2337/db08-1504