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Allelic Depletion of grem1 Attenuates Diabetic Kidney Disease

OBJECTIVE: Gremlin (grem1) is an antagonist of the bone morphogenetic protein family that plays a key role in limb bud development and kidney formation. There is a growing appreciation that altered grem1 expression may regulate the homeostatic constraints on damage responses in diseases such as diab...

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Detalles Bibliográficos
Autores principales: Roxburgh, Sarah A., Kattla, Jayesh J., Curran, Simon P., O'Meara, Yvonne M., Pollock, Carol A., Goldschmeding, Roel, Godson, Catherine, Martin, Finian, Brazil, Derek P.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699858/
https://www.ncbi.nlm.nih.gov/pubmed/19401426
http://dx.doi.org/10.2337/db08-1365