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Allelic Depletion of grem1 Attenuates Diabetic Kidney Disease
OBJECTIVE: Gremlin (grem1) is an antagonist of the bone morphogenetic protein family that plays a key role in limb bud development and kidney formation. There is a growing appreciation that altered grem1 expression may regulate the homeostatic constraints on damage responses in diseases such as diab...
Autores principales: | Roxburgh, Sarah A., Kattla, Jayesh J., Curran, Simon P., O'Meara, Yvonne M., Pollock, Carol A., Goldschmeding, Roel, Godson, Catherine, Martin, Finian, Brazil, Derek P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699858/ https://www.ncbi.nlm.nih.gov/pubmed/19401426 http://dx.doi.org/10.2337/db08-1365 |
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