Beneficial Endocrine but Adverse Exocrine Effects of Sitagliptin in the Human Islet Amyloid Polypeptide Transgenic Rat Model of Type 2 Diabetes: Interactions With Metformin

OBJECTIVE: We sought to establish the extent and mechanisms by which sitagliptin and metformin singly and in combination modify islet disease progression in human islet amyloid polypeptide transgenic (HIP) rats, a model for type 2 diabetes. RESEARCH DESIGN AND METHODS: HIP rats were treated with sit...

Descripción completa

Detalles Bibliográficos
Autores principales: Matveyenko, Aleksey V., Dry, Sarah, Cox, Heather I., Moshtaghian, Artemis, Gurlo, Tatyana, Galasso, Ryan, Butler, Alexandra E., Butler, Peter C.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699878/
https://www.ncbi.nlm.nih.gov/pubmed/19403868
http://dx.doi.org/10.2337/db09-0058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699878/
https://www.ncbi.nlm.nih.gov/pubmed/19403868
http://dx.doi.org/10.2337/db09-0058

Ejemplares similares