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Human Neutrophil Elastase Responsive Delivery from Poly(ethylene glycol) Hydrogels

[Image: see text] A novel enzyme-responsive hydrogel drug delivery system was developed with the potential to treat inflammation locally. Human neutrophil elastase (HNE) is a serine protease secreted by neutrophils which are the first cells recruited to inflammatory sites. We exploited this cell-sec...

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Detalles Bibliográficos
Autores principales: Aimetti, Alex A., Tibbitt, Mark W., Anseth, Kristi S.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699883/
https://www.ncbi.nlm.nih.gov/pubmed/19408953
http://dx.doi.org/10.1021/bm9000926