Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA

BACKGROUND: Host restriction factor APOBEC3G (A3G) blocks human immunodeficiency virus type 1 (HIV-1) replication by G-to-A hypermutation, and by inhibiting DNA synthesis and provirus formation. Previous reports have suggested that A3G is a dimer and its virion incorporation is mediated through inte...

Descripción completa

Detalles Bibliográficos
Autores principales: Friew, Yeshitila N, Boyko, Vitaly, Hu, Wei-Shau, Pathak, Vinay K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700067/
https://www.ncbi.nlm.nih.gov/pubmed/19497112
http://dx.doi.org/10.1186/1742-4690-6-56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700067/
https://www.ncbi.nlm.nih.gov/pubmed/19497112
http://dx.doi.org/10.1186/1742-4690-6-56

Ejemplares similares