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Tbx1 and Brn4 regulate retinoic acid metabolic genes during cochlear morphogenesis

BACKGROUND: In vertebrates, the inner ear is comprised of the cochlea and vestibular system, which develop from the otic vesicle. This process is regulated via inductive interactions from surrounding tissues. Tbx1, the gene responsible for velo-cardio-facial syndrome/DiGeorge syndrome in humans, is...

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Detalles Bibliográficos
Autores principales: Braunstein, Evan M, Monks, Dennis C, Aggarwal, Vimla S, Arnold, Jelena S, Morrow, Bernice E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700094/
https://www.ncbi.nlm.nih.gov/pubmed/19476657
http://dx.doi.org/10.1186/1471-213X-9-31