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Intragraft Selection of the T Cell Receptor Repertoire by Class I MHC Sequences in Tolerant Recipients
BACKGROUND: Allograft tolerance of ACI (RT1(a)) recipients to WF (RT1(u)) hearts can be induced by allochimeric class I MHC molecules containing donor-type (RT1A(u)) immunogenic epitopes displayed on recipient-type (RT1A(a)) sequences. Here, we sought the mechanisms by which allochimeric sequences m...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700265/ https://www.ncbi.nlm.nih.gov/pubmed/19562081 http://dx.doi.org/10.1371/journal.pone.0006076 |