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Intragraft Selection of the T Cell Receptor Repertoire by Class I MHC Sequences in Tolerant Recipients

BACKGROUND: Allograft tolerance of ACI (RT1(a)) recipients to WF (RT1(u)) hearts can be induced by allochimeric class I MHC molecules containing donor-type (RT1A(u)) immunogenic epitopes displayed on recipient-type (RT1A(a)) sequences. Here, we sought the mechanisms by which allochimeric sequences m...

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Detalles Bibliográficos
Autores principales:	Liu, Dahai, Shen, Xiu-Da, Zhai, Yuan, Lam, Wengsi, Liao, Jingying, Busuttil, Ronald W., Ghobrial, Rafik M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700265/ https://www.ncbi.nlm.nih.gov/pubmed/19562081 http://dx.doi.org/10.1371/journal.pone.0006076

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