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Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells

There is evidence that pluripotency of mouse embryonic stem (ES) cells is associated with the activity of a network of transcription factors with Sox2, Oct4, and Nanog at the core. Using fluorescent reporters for the expression of Nanog, we observed that a population of ES cells is best described by...

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Detalles Bibliográficos
Autores principales: Kalmar, Tibor, Lim, Chea, Hayward, Penelope, Muñoz-Descalzo, Silvia, Nichols, Jennifer, Garcia-Ojalvo, Jordi, Martinez Arias, Alfonso
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700273/
https://www.ncbi.nlm.nih.gov/pubmed/19582141
http://dx.doi.org/10.1371/journal.pbio.1000149