Mre11-Rad50 Promotes Rapid Repair of DNA Damage in the Polyploid Archaeon Haloferax volcanii by Restraining Homologous Recombination

Polyploidy is frequent in nature and is a hallmark of cancer cells, but little is known about the strategy of DNA repair in polyploid organisms. We have studied DNA repair in the polyploid archaeon Haloferax volcanii, which contains up to 20 genome copies. We have focused on the role of Mre11 and Ra...

Descripción completa

Detalles Bibliográficos
Autores principales: Delmas, Stéphane, Shunburne, Lee, Ngo, Hien-Ping, Allers, Thorsten
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700283/
https://www.ncbi.nlm.nih.gov/pubmed/19593371
http://dx.doi.org/10.1371/journal.pgen.1000552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700283/
https://www.ncbi.nlm.nih.gov/pubmed/19593371
http://dx.doi.org/10.1371/journal.pgen.1000552

Ejemplares similares