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Acquisition of Cell–Cell Fusion Activity by Amino Acid Substitutions in Spike Protein Determines the Infectivity of a Coronavirus in Cultured Cells

Coronavirus host and cell specificities are determined by specific interactions between the viral spike (S) protein and host cell receptor(s). Avian coronavirus infectious bronchitis (IBV) has been adapted to embryonated chicken eggs, primary chicken kidney (CK) cells, monkey kidney cell line Vero,...

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Detalles Bibliográficos
Autores principales: Yamada, Yoshiyuki, Liu, Xiao Bo, Fang, Shou Guo, Tay, Felicia P. L., Liu, Ding Xiang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700284/
https://www.ncbi.nlm.nih.gov/pubmed/19572016
http://dx.doi.org/10.1371/journal.pone.0006130