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Apparent dependence of protein evolutionary rate on number of interactions is linked to biases in protein–protein interactions data sets
BACKGROUND: Several studies have suggested that proteins that interact with more partners evolve more slowly. The strength and validity of this association has been called into question. Here we investigate how biases in high-throughput protein–protein interaction studies could lead to a spurious co...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270031/ https://www.ncbi.nlm.nih.gov/pubmed/14525624 http://dx.doi.org/10.1186/1471-2148-3-21 |