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A c-Myc–SIRT1 feedback loop regulates cell growth and transformation
The protein deacetylase SIRT1 has been implicated in a variety of cellular functions, including development, cellular stress responses, and metabolism. Increasing evidence suggests that similar to its counterpart, Sir2, in yeast, Caenorhabditis elegans, and Drosophila melanogaster, SIRT1 may functio...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700370/ https://www.ncbi.nlm.nih.gov/pubmed/19364925 http://dx.doi.org/10.1083/jcb.200809167 |