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Inactivation of Chibby affects function of motile airway cilia
Chibby (Cby) is a conserved component of the Wnt–β-catenin pathway. Cby physically interacts with β-catenin to repress its activation of transcription. To elucidate the function of Cby in vertebrates, we generated Cby(−/−) mice and found that after 2–3 d of weight loss, the majority of mice die befo...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700371/ https://www.ncbi.nlm.nih.gov/pubmed/19364920 http://dx.doi.org/10.1083/jcb.200809144 |