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Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis

Sam68 is a KH-type RNA-binding protein involved in several steps of RNA metabolism with potential implications in cell differentiation and cancer. However, its physiological roles are still poorly understood. Herein, we show that Sam68(−/−) male mice are infertile and display several defects in sper...

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Detalles Bibliográficos
Autores principales: Paronetto, Maria Paola, Messina, Valeria, Bianchi, Enrica, Barchi, Marco, Vogel, Gillian, Moretti, Costanzo, Palombi, Fioretta, Stefanini, Mario, Geremia, Raffaele, Richard, Stéphane, Sette, Claudio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700383/
https://www.ncbi.nlm.nih.gov/pubmed/19380878
http://dx.doi.org/10.1083/jcb.200811138