Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae

We studied the function of the cyclin-dependent kinase Cdc28 (Cdk1) in the DNA damage response and maintenance of genome stability using Saccharomyces cerevisiae. Reduced Cdc28 activity sensitizes cells to chronic DNA damage, but Cdc28 is not required for cell viability upon acute exposure to DNA-da...

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Detalles Bibliográficos
Autores principales: Enserink, Jorrit M., Hombauer, Hans, Huang, Meng-Er, Kolodner, Richard D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700387/
https://www.ncbi.nlm.nih.gov/pubmed/19398760
http://dx.doi.org/10.1083/jcb.200811083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700387/
https://www.ncbi.nlm.nih.gov/pubmed/19398760
http://dx.doi.org/10.1083/jcb.200811083

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