Synaptic activity prompts γ-secretase–mediated cleavage of EphA4 and dendritic spine formation

Alzheimer's disease is an age-dependent neurodegenerative disorder that is characterized by a progressive decline in cognitive function. γ-secretase dysfunction is evident in many cases of early onset familial Alzheimer's disease. However, the mechanism by which γ-secretase dysfunction res...

Descripción completa

Detalles Bibliográficos
Autores principales: Inoue, Eiji, Deguchi-Tawarada, Maki, Togawa, Aki, Matsui, Chiyuki, Arita, Kohei, Katahira-Tayama, Sayaka, Sato, Toshitaka, Yamauchi, Emiko, Oda, Yoshiya, Takai, Yoshimi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700400/
https://www.ncbi.nlm.nih.gov/pubmed/19414612
http://dx.doi.org/10.1083/jcb.200809151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700400/
https://www.ncbi.nlm.nih.gov/pubmed/19414612
http://dx.doi.org/10.1083/jcb.200809151

Ejemplares similares