Adenoviral expression of a transforming growth factor-β1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated rats

BACKGROUND: Transforming growth factor-β (TGF-β) is a key mediator in establishing liver fibrosis. Therefore, TGF-β as a causative agent may serve as a primary target for antifibrotic gene therapy approaches. We have previously shown that the adenoviral delivery of a transgene constitutively express...

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Detalles Bibliográficos
Autores principales: Arias, Monica, Sauer-Lehnen, Sibille, Treptau, Jens, Janoschek, Nora, Theuerkauf, Ingo, Buettner, Reinhard, Gressner, Axel M, Weiskirchen, Ralf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270053/
https://www.ncbi.nlm.nih.gov/pubmed/14565855
http://dx.doi.org/10.1186/1471-230X-3-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270053/
https://www.ncbi.nlm.nih.gov/pubmed/14565855
http://dx.doi.org/10.1186/1471-230X-3-29

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