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Adenoviral expression of a transforming growth factor-β1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated rats

BACKGROUND: Transforming growth factor-β (TGF-β) is a key mediator in establishing liver fibrosis. Therefore, TGF-β as a causative agent may serve as a primary target for antifibrotic gene therapy approaches. We have previously shown that the adenoviral delivery of a transgene constitutively express...

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Detalles Bibliográficos
Autores principales:	Arias, Monica, Sauer-Lehnen, Sibille, Treptau, Jens, Janoschek, Nora, Theuerkauf, Ingo, Buettner, Reinhard, Gressner, Axel M, Weiskirchen, Ralf
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2003
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270053/ https://www.ncbi.nlm.nih.gov/pubmed/14565855 http://dx.doi.org/10.1186/1471-230X-3-29

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