Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase

BACKGROUND: Bloom syndrome is one of the most cancer-predisposing disorders and is characterized by genomic instability and a high frequency of sister chromatid exchange. The disorder is caused by loss of function of a 3' to 5' RecQ DNA helicase, BLM. The exact role of BLM in maintaining g...

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Detalles Bibliográficos
Autores principales: Schawalder, James, Paric, Enesa, Neff, Norma F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270065/
https://www.ncbi.nlm.nih.gov/pubmed/14577841
http://dx.doi.org/10.1186/1471-2121-4-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270065/
https://www.ncbi.nlm.nih.gov/pubmed/14577841
http://dx.doi.org/10.1186/1471-2121-4-15

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