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Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase
BACKGROUND: Bloom syndrome is one of the most cancer-predisposing disorders and is characterized by genomic instability and a high frequency of sister chromatid exchange. The disorder is caused by loss of function of a 3' to 5' RecQ DNA helicase, BLM. The exact role of BLM in maintaining g...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270065/ https://www.ncbi.nlm.nih.gov/pubmed/14577841 http://dx.doi.org/10.1186/1471-2121-4-15 |