A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells

BACKGROUND: In Arabidopsis thaliana, the gene Tousled encodes a protein kinase of unknown function, but mutations in the gene lead to flowering and leaf morphology defects. We have recently cloned a mammalian Tousled-Like Kinase (TLK1B) and found that it phosphorylates specifically histone H3, in vi...

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Detalles Bibliográficos
Autores principales: Sunavala-Dossabhoy, Gulshan, Li, Yuan, Williams, Briana, De Benedetti, Arrigo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270066/
https://www.ncbi.nlm.nih.gov/pubmed/14583098
http://dx.doi.org/10.1186/1471-2121-4-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270066/
https://www.ncbi.nlm.nih.gov/pubmed/14583098
http://dx.doi.org/10.1186/1471-2121-4-16

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