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A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells
BACKGROUND: In Arabidopsis thaliana, the gene Tousled encodes a protein kinase of unknown function, but mutations in the gene lead to flowering and leaf morphology defects. We have recently cloned a mammalian Tousled-Like Kinase (TLK1B) and found that it phosphorylates specifically histone H3, in vi...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270066/ https://www.ncbi.nlm.nih.gov/pubmed/14583098 http://dx.doi.org/10.1186/1471-2121-4-16 |