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Increased levels of soluble CD226 in sera accompanied by decreased membrane CD226 expression on peripheral blood mononuclear cells from cancer patients

BACKGROUND: As a cellular membrane triggering receptor, CD226 is involved in the NK cell- or CTL-mediated lysis of tumor cells of different origin, including freshly isolated tumor cells and tumor cell lines. Here, we evaluated soluble CD226 (sCD226) levels in sera, and membrane CD226 (mCD226) expre...

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Detalles Bibliográficos
Autores principales: Xu, Zhuwei, Zhang, Tao, Zhuang, Ran, Zhang, Yun, Jia, Wei, Song, Chaojun, Yang, Kun, Yang, Angang, Jin, Boquan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700819/
https://www.ncbi.nlm.nih.gov/pubmed/19490613
http://dx.doi.org/10.1186/1471-2172-10-34