dRecQ4 Is Required for DNA Synthesis and Essential for Cell Proliferation in Drosophila

BACKGROUND: The family of RecQ DNA helicases plays an important role in the maintenance of genomic integrity. Mutations in three of the five known RecQ family members in humans, BLM, WRN and RecQ4, lead to disorders that are characterized by predisposition to cancer and premature aging. METHODOLOGY/...

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Detalles Bibliográficos
Autores principales: Xu, Yanjuan, Lei, Zhiyong, Huang, Hai, Dui, Wen, Liang, Xuehong, Ma, Jun, Jiao, Renjie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700968/
https://www.ncbi.nlm.nih.gov/pubmed/19572017
http://dx.doi.org/10.1371/journal.pone.0006107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700968/
https://www.ncbi.nlm.nih.gov/pubmed/19572017
http://dx.doi.org/10.1371/journal.pone.0006107

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