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Porcine CD18 mediates Actinobacillus pleuropneumoniae ApxIII species-specific toxicity

Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, produces Apx toxins that are recognized as major virulence factors. Recently, we showed that ApxIIIA-cytotoxic activity specifically targets Sus scrofa leukocytes. Since both LtxA from Aggregatibacter actinomycetemcomit...

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Detalles Bibliográficos
Autores principales: Vanden Bergh, Philippe G.A.C., Zecchinon, Laurent L.M., Fett, Thomas, Desmecht, Daniel
Formato: Texto
Lenguaje:English
Publicado: EDP Sciences 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701182/
https://www.ncbi.nlm.nih.gov/pubmed/19356397
http://dx.doi.org/10.1051/vetres/2009016