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Common variants at ten loci influence myocardial repolarization: the QTGEN consortium

QT interval duration reflecting myocardial repolarization on the electrocardiogram is a heritable risk factor for sudden cardiac death and drug-induced arrhythmias. We conducted a meta-analysis of 3 genome-wide association studies in 13,685 individuals of European ancestry from the Framingham Heart...

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Detalles Bibliográficos
Autores principales: Newton-Cheh, Christopher, Eijgelsheim, Mark, Rice, Kenneth, de Bakker, Paul I. W., Yin, Xiaoyan, Estrada, Karol, Bis, Joshua, Marciante, Kristin, Rivadeneira, Fernando, Noseworthy, Peter A., Sotoodehnia, Nona, Smith, Nicholas L., Rotter, Jerome I., Kors, Jan A., Witteman, Jacqueline C.M., Hofman, Albert, Heckbert, Susan R., O’Donnell, Christopher J., Uitterlinden, Andre G., Psaty, Bruce M., Lumley, Thomas, Larson, Martin G., Stricker, Bruno H.Ch.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701449/
https://www.ncbi.nlm.nih.gov/pubmed/19305408
http://dx.doi.org/10.1038/ng.364