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Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle

While numerous hypotheses have been proposed to explain the molecular mechanisms underlying the pathogenesis of neurodegenerative diseases, the theory of oxidative stress has received considerable support. Although many correlations have been established and encouraging evidence has been obtained, c...

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Detalles Bibliográficos
Autores principales: Malkus, Kristen A, Tsika, Elpida, Ischiropoulos, Harry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701947/
https://www.ncbi.nlm.nih.gov/pubmed/19500376
http://dx.doi.org/10.1186/1750-1326-4-24