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Docosahexaenoic acid inhibits protein kinase C translocation/activation and cardiac hypertrophy in rat cardiomyocytes

Phenylephrine (PE) induces cardiac hypertrophy through multiple signaling pathways including pathways involving protein kinase C (PKC) activation. Docosahexaenoic acid (DHA), an omega-3 fatty acid, has been shown to reduce the PE-induced hypertrophic responses. However, the effects of DHA on PKC act...

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Detalles Bibliográficos
Autores principales: Castillo, Alicia, Ruzmetov, Nargiz, Harvey, Kevin A, Stillwell, William, Zaloga, Gary P, Siddiqui, Rafat A
Formato: Texto
Lenguaje:English
Publicado: Library Publishing Media 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702061/
https://www.ncbi.nlm.nih.gov/pubmed/19565009