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Ab initio base fragment molecular orbital studies of influenza viral hemagglutinin HA1 full-domains in complex with sialoside receptors

Mutations in avian influenza A viral hemagglutinin HA1 domain may alter the binding specificity of HA for α-sialosaccharide receptors, shifting the virus's host range from birds to humans. The amino acid mutations can occur at the sialoside binding site, as well as the antigenic site, far from...

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Detalles Bibliográficos
Autores principales: Sawada, Toshihiko, Hashimoto, Tomohiro, Tokiwa, Hiroaki, Suzuki, Tohru, Nakano, Hirofumi, Ishida, Hideharu, Kiso, Makoto, Suzuki, Yasuo
Formato: Texto
Lenguaje:English
Publicado: Library Publishing Media 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702072/
https://www.ncbi.nlm.nih.gov/pubmed/19565017