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Ab initio base fragment molecular orbital studies of influenza viral hemagglutinin HA1 full-domains in complex with sialoside receptors
Mutations in avian influenza A viral hemagglutinin HA1 domain may alter the binding specificity of HA for α-sialosaccharide receptors, shifting the virus's host range from birds to humans. The amino acid mutations can occur at the sialoside binding site, as well as the antigenic site, far from...
Autores principales: | Sawada, Toshihiko, Hashimoto, Tomohiro, Tokiwa, Hiroaki, Suzuki, Tohru, Nakano, Hirofumi, Ishida, Hideharu, Kiso, Makoto, Suzuki, Yasuo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Library Publishing Media
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702072/ https://www.ncbi.nlm.nih.gov/pubmed/19565017 |
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